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Many people with asthma also have gastroesophageal reflux

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disease, or GERD. The study, which was funded by the American Lung Association and the U.S. "Our study sho this is not an effective practice," Wise said. "If you have questions or concerns because you're taking Nexium or another proton pump inhibitor, talk to your doctor."
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The U.S. The diaphragm may overinflate, and the extra pressure may
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cause the esophageal sphincter to herniate, allowing fluids to bentlee out of the stomach. National Heart, Lung, and Blood Institute has more on asthma treatments.. Proton pump inhibitors work by suppressing acid production.

To reduce that possibility,

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doctors have been prescribing acid-suppressing medications known as proton pump inhibitors (PPI). And asthma might trigger GERD when it causes difficulty breathing. "These drugs are effective for treating heartburn,
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and if you have asthma and heartburn, then these drugs may well be used for those symptoms."
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Wise said the researchers were not advocating that anyone stop taking their medications, but that they should talk with their physicians. "People need to follow their doctor's advice and take
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their asthma medications on a regular basis," he said. All had either no symptoms or just minimal symptoms of GERD. There was no statistically significant difference between those who took Nexium and the placebo group with respect to
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asthma control, lung function, GERD symptoms, night awakenings and quality of life, the study found. Doctors have suspected
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that if people with asthma breathe in during reflux, they might breathe irritating stomach fluids into the lungs.

The rate of asthma events was 2.3 per person-year for the placebo group and 2.5 events per person-year for the treatment group. Although the two conditions may seem quite

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different, doctors have long suspected that they're linked, with each disorder possibly triggering the other. But a study in
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the issue of the New England Journal of Medicine repots that a PPI probably isn't
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going to help lessen wheezing in people with silent GERD. But some people have what's known as silent GERD, meaning they have no symptoms. In most people, he said, a 40-mg dose would suppress nearly all acid production in the stomach.

National Institutes of Health, included

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412 people whose asthma was badly controlled even though they were being treated with inhaled corticosteroids. "Patients
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with asthma that is not adequately controlled with the usual asthma medications, and who have no symptoms of heartburn, but who may or may not have silent GERD, don't seem to have any improvement of asthma when treated
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(Nexium)," said one of the study's authors, Dr. Acid Reducers May Not Help All With Asthma -- Acid-suppressing medications won't ease asthma symptoms if you don't have heartburn symptoms, too, a new study has found. They took 40 milligrams of Nexium or a placebo twice a day. Acid reflux might cause asthma symptoms through aspiration of fluid into the airways, or acid
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might irritate the esophagus and upper airway, according to the study. "The vast use is around treatment of GERD and heartburn," he said. "For those who have asthma and have GERD, we want to make sure they continue
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to take their medications as directed," Hains said.

Robert Wise, a professor of medicine in the division of pulmonary and critical care medicine at Johns Hopkins University School of Medicine in Baltimore. Ruddy Hains, a spokesman for AstraZeneca, which makes Nexium, said that the drug is not indicated for use in asthma and asymptomatic GERD. According to Wise, people given the drug took a larger-than-standard dose.

 










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